Can Anabolic Steroids Cause Fatty Liver?
November 8, 2023 | by Yashaswi Pathakamuri | Posted in FAQ's
Yes, the use of anabolic steroids, particularly when taken in excessive or prolonged amounts, can contribute to the development of fatty liver disease, specifically a condition called “anabolic steroid-induced hepatotoxicity.” Fatty liver disease occurs when fat accumulates in liver cells, and it can be caused by various factors, including the use of certain drugs, like anabolic steroids.
The mechanisms by which anabolic steroids can lead to fatty liver disease are not completely understood, but several factors may be involved:
- Altered Lipid Metabolism: Anabolic steroids can affect lipid (fat) metabolism, leading to increased levels of lipids in the bloodstream. This can result in the accumulation of fat in liver cells.
- Reduced Liver Enzyme Activity: Anabolic steroids can affect the activity of liver enzymes responsible for metabolizing substances in the body. This can disrupt the normal processing of fats and lead to their accumulation in the liver.
- Decreased HDL Cholesterol: Anabolic steroids can lower the levels of high-density lipoprotein (HDL) cholesterol, the “good” cholesterol. This can further contribute to fat buildup in the liver.
- Insulin Resistance: Some studies suggest that anabolic steroids may lead to insulin resistance, which can promote fatty liver disease.
It’s important to note that not everyone who uses anabolic steroids will develop fatty liver disease, and the risk may vary depending on factors like the duration and dosage of steroid use, an individual’s overall health, and genetics. Additionally, other factors such as diet and alcohol consumption can also influence the development of fatty liver disease.
Fatty liver disease can progress from a benign condition (non-alcoholic fatty liver disease or NAFLD) to more severe forms, including non-alcoholic steatohepatitis (NASH) and cirrhosis, which are associated with inflammation and liver damage. Therefore, if you are using anabolic steroids or are concerned about your liver health due to their use, it’s important to consult a healthcare provider for evaluation and guidance. They can assess your liver health, provide recommendations, and monitor for any potential liver-related issues.