What are the Symptoms of Adrenal Adenoma?

Adrenal adenoma is a non-cancerous (benign) tumor that forms in the adrenal glands, which are located on top of the kidneys. Adrenal adenomas often do not cause noticeable symptoms and are usually discovered incidentally during imaging tests done for other reasons. However, in some cases, they may produce excess hormones, leading to various symptoms. Common symptoms associated with adrenal adenoma, depending on the hormone(s) being overproduced, may include:

  1. High Blood Pressure (Hypertension):
    • Elevated blood pressure due to excess production of aldosterone (primary aldosteronism).
  2. Muscle Weakness and Fatigue:
    • Weakness, fatigue, and decreased stamina, often due to excessive cortisol production (Cushing’s syndrome).
  3. Weight Gain and Central Obesity:
    • Weight gain, especially in the abdomen (central obesity), and difficulty losing weight, associated with cortisol excess.
  4. Increased Thirst and Urination:
    • Increased thirst (polydipsia) and urination (polyuria), often due to excessive production of vasopressin or anti-diuretic hormone (ADH).
  5. Excessive Hair Growth (Hirsutism):
    • Unwanted hair growth in women, particularly on the face, chest, back, and abdomen, related to excess androgen production (e.g., testosterone).
  6. Irregular Menstrual Periods:
    • Irregular menstrual periods or absent menstruation (amenorrhea) in women, caused by hormonal imbalances.
  7. Osteoporosis or Bone Fragility:
    • Weakened bones, brittle bones, or increased susceptibility to fractures due to alterations in calcium and bone metabolism.
  8. Easy Bruising and Thin Skin:
    • Increased susceptibility to bruising, thinning of the skin, and slower wound healing, associated with glucocorticoid excess.
  9. Depression and Mood Swings:
    • Mood changes, irritability, depression, or anxiety due to hormonal imbalances affecting the brain.
  10. Palpitations or Rapid Heartbeat:
    • Feeling of a racing or irregular heartbeat, related to excess production of adrenaline or other catecholamines.

It’s important to note that not all adrenal adenomas cause symptoms, and the symptoms can vary based on the size of the adenoma, its hormone production, and individual factors. If you suspect you may have adrenal adenoma or are experiencing related symptoms, it’s essential to consult a healthcare professional for a thorough evaluation, diagnosis, and appropriate management.

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