How DHT Causes Hair Loss?

Women Worried With Hair loss

Dihydrotestosterone (DHT) is a hormone that plays a significant role in hair loss, particularly in individuals with a genetic predisposition to androgenetic alopecia, also known as male or female pattern baldness. Here’s how DHT contributes to hair loss:

  • Genetic Predisposition: In individuals with a genetic predisposition to androgenetic alopecia, hair follicles are sensitive to the effects of DHT. This genetic sensitivity is inherited and can lead to hair loss.
  • Conversion of Testosterone: DHT is derived from testosterone, the primary male sex hormone. An enzyme called 5-alpha-reductase converts testosterone into DHT. When there is an excessive amount of DHT in the body or when hair follicles are particularly sensitive to it, it can affect the hair growth cycle.
  • Miniaturization of Hair Follicles: DHT can shrink or miniaturize hair follicles over time. This process is called follicular miniaturization. As the hair follicles become smaller and finer, they produce shorter and thinner hair strands, which eventually cease to grow.
  • Shortened Hair Growth Cycle: DHT can also shorten the growth phase (anagen) of the hair follicles. This means that affected hair follicles spend less time actively growing and more time in the resting phase (telogen). As a result, hair loss occurs because the affected follicles produce shorter and less robust hair, leading to a noticeable decrease in hair density.

It’s important to understand that not everyone with a genetic predisposition to androgenetic alopecia will experience hair loss to the same degree. The extent and pattern of hair loss can vary among individuals. Additionally, not all hair loss is solely due to DHT, as other factors can also contribute to hair loss, such as hormonal imbalances, medical conditions, medications, and lifestyle choices.

Treatment options for hair loss related to DHT typically involve medications that inhibit the production of DHT or block its effects on hair follicles. These treatments are available by prescription and can help slow down hair loss and promote hair regrowth in some cases. If you are concerned about hair loss, it’s advisable to consult a healthcare professional or dermatologist who can assess your condition and recommend appropriate treatments.

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