What Gene Causes Asthma?
March 25, 2024 | by Yashaswi Pathakamuri | Posted in FAQ's
Asthma is a complex condition influenced by both genetic and environmental factors. While there isn’t a single gene that causes asthma, there are genetic variations that can predispose individuals to develop asthma. Several genes have been identified as potential contributors to asthma susceptibility, including:
- ADAM33: This gene has been associated with airway remodeling and smooth muscle hyperplasia, which are characteristics of asthma.
- ORMDL3: Variations in this gene have been linked to increased risk of childhood asthma and altered immune responses.
- IL4, IL13: Genes encoding interleukins (IL-4 and IL-13) are involved in immune regulation and inflammation and have been associated with asthma susceptibility.
- IL-5, IL-9, IL-17: Other interleukin genes have also been implicated in asthma susceptibility due to their roles in immune responses and inflammation.
- HLA genes: Genes within the human leukocyte antigen (HLA) complex, which plays a key role in the immune system, have been linked to asthma susceptibility.
- GST genes: Genes encoding glutathione S-transferases (GSTs), involved in detoxification processes, have been associated with asthma risk due to their role in protecting against oxidative stress.
- ADRB2: This gene encodes the beta-2 adrenergic receptor, which plays a role in bronchodilation. Variants in this gene have been associated with asthma susceptibility and response to asthma medications.
It’s important to note that having variations in these genes doesn’t guarantee that someone will develop asthma. Environmental factors, such as exposure to allergens, pollutants, respiratory infections, and lifestyle factors, also play significant roles in the development and exacerbation of asthma. Therefore, asthma is considered a multifactorial condition resulting from a complex interplay between genetic predisposition and environmental influences.
Recent Posts
Categories
- Arthritis
- B vitamins
- Berries
- Best time to take
- Breasfeeding
- cancer
- Chronic Diseases
- COVID-19
- Dairy
- Deficiency
- Diabetes
- Diet
- Diseases
- FAQ's
- Fats
- Fever
- Hair
- health
- Kidney
- Leafy Vegetables
- Lung disease
- mango
- Meat
- Millets
- Minerals
- Myositis
- Nausea
- Nutrition Facts
- Nuts and Seeds
- Oats and Oatmeal
- Psoriasis
- Recipes
- Rice
- Skin
- spices and Condiments
- Summer
- Thyroid
- Varicose Veins
- Vegetables
- Vitamins
- Vomiting
- water
- weight gain
- weight Loss
Archives
- May 2024
- April 2024
- March 2024
- February 2024
- January 2024
- December 2023
- November 2023
- October 2023
- September 2023
- August 2023
- July 2023
- June 2023
- May 2023
- April 2023
- March 2023
- February 2023
- January 2023
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- February 2022
- January 2022
- December 2021
- November 2021
- October 2021
- September 2021
- July 2021
- June 2021
- May 2021
- April 2021
- March 2021
- February 2021
- January 2021
- December 2020
- November 2020
- October 2020
- September 2020
- August 2020
- July 2020
- June 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020